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The levels of CYP27A1 and CYP27B1 were significantly upregulated along with those of VDR mRNA, but CYP24A1 was downregulated in groups supplemented with GSH or its precursor (Fig

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Most common side effects of GHSs The potential side effects of GH secretagogues depend on the specific compound and may include: local reactions at the injection site fractal flushing nausea and digestive issues increased appetite and weight gain elevated prolactin levels elevated cortisol levels insulin resistance water retention All GHSs except Ibutamoren are applied via injections, which can lead to local adverse reactions such as pain, swelling, and redness at the injection site